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Mac Callum classified viral hepatitis into two types: 1) Viral hepatitis A
(infectious hepatitis), and 2) Viral hepatitis B (serum hepatitis).
Blumberg discovered Australia antigen (HBsAg) in aborigines in 1965.
Dane discovered complete HBV particle (Dane particle) in 1970 followed by
discovery of HBeAg by Magnius in 1972. In 1973, Feinstone and Purcell
identified HAV. Rizzetto described delta antigen (HDV) in 1977.
Balayan proved HEV in 1983 from the specimen obtained during 1955~1956
massive epidemic of water-borne hepatitis in Delhi, India. After years of
silence, Chiron group cloned and identified HCV in 1988. In 1995 and 1996,
Abbott group and Genelab group reported discovery of GBV-C and HGV
respectively, and was proved to be the same virus.
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